Tel. +34 913941777
Faculty of Pharmacy, Complutense University of Madrid
Pl. de Ramón y Cajal, s/n, 28040 Madrid
The group was created in 2005, in order to be recognised by the CAM/UCM (920384). In recent years, new tissue-specific murine models of insulin resistance have been developed to study the compensatory mechanisms of insulin resistance in relation to pancreatic beta-cell hyperplasia and its impact on cardiovascular complications. We are also developing new murine models that develop a malformation/dysfunction of brown adipose tissue that alters energy balance and metabolic efficiency, and its diabetogenic metabolic complications. In parallel, we have developed new cardiovascular cell models to study the mechanisms of insulin resistance in relation to signals associated with pro-inflammatory processes and vascular injury.
Molecular mechanisms in the progression of type II diabetes
Thermogenic function and inflammatory adipose organ disease