Strategic objectives

  • To participate with multidisciplinary groups in European projects
  • To maintain funding to develop priority research studies in the fields of food, nutrition, and health
  • To be able to maintain and carry out intervention studies in at-risk populations to prevent the development of degenerative diseases

Lines of research

Nutrition and diet in the prevention of cardiovascular diseases

Since 1979, the team has been investigating the possible role of fat and other dietary components (salt, fibre, protein, minerals, etc.) on lipoprotein metabolism and their influence on the subsequent development of CVD. Our research extends from neonates to the elderly. Thus, our team has participated and continues to participate in different studies “Área de Toledo” and “La Serena” in neonatal populations, “Fuerzas Armadas” in healthy adults, “AVENA” in the adolescent population, “Lerma” in peri-menopause women, etc., relating nutritional and anthropometric aspects with cardiovascular risk factors, obtaining very novel results for the international bibliography. Currently, this group has initiated studies in the search for early hormonal and lipoprotein markers of metabolic syndrome (MS) and is also interested in gene-diet interactions in cardiovascular disease (CVD). The leading role of genetic load in these degenerative diseases is accepted (Bouchard, 2011; Ordovás, 2011), and our group (Gesteiro et al., 2011) found differences at birth in markers of insulin sensitivity associated with different polymorphisms of the apolipoprotein (Apo) A-5 gene (a candidate gene to explain lipoprotein alterations). Therefore, we believe it is essential to study the influence of the genetic interaction between neonate*mother of certain candidate genes on lipoprotein markers and insulin resistance/sensitivity in neonates in order to predict the prevalence of MS in the population. Publications:

Functional Foods in Health: Nutrigenetics and Nutrigenomics

Our group has been conducting research following my collaboration in the Framing Study (Gene-diet interaction in elderly from the Framingham Study consuming Mediterranean or typical American diets, National Institute of Health (USA) in this novel field. My training in the field of “gene-diet” interaction took place under the tutelage of Prof. Ordovas and Prof. Schaefer, who are internationally renowned in the field of nutrition, genetics, and cardiovascular diseases. I was the researcher responsible for two projects studying the role of some candidate genes on the effects of phytosterols on lipoprotein metabolism in different population groups. With this work, this new line of research, in which my team is currently participating in different projects that analyse the potential benefits of the inclusion of functional meat products in the diet (“Red Consolider Ingenio” 2010-16), on cardiovascular risk markers, and the influence of “candidate gene” mutations on these effects, with the aim of promoting the development of “Personalised Nutrition”. Publications:

Other members of the group