Immune-monitoring of Cancer and Immune-mediated Pathologies Unit (UICPI)

Services offered

  • Immunophenotyping and functional study of antigen-specific subpopulations: activation, proliferation, cytokine production, Th1/Th2/Th17, among others.
  • Phenotypic and phosphoflow analysis (flow cytometry)
  • Study of TRECs in screening for secondary immunodeficiencies.
  • Cytokine and chemokine profiling studies after antigen-specific stimulation.
  • Inflammation vs. immunoregulation (Luminex)
  • Studies of secondary and primary immunodeficiencies associated with malignancy:
    Typing of the pathological immunophenotype and prediction of risk associated with immunodeficiency and monitoring of response to treatment.
  • Specific immune response to target antigens:
    Lymphoproliferative and antigen-specific cell stimulation studies.
    Antigen-specific cytotoxicity studies.
    Tetramer or pentamer assays for specific HLA-restricted response.
    Study of specific cell populations for the development of vaccines or tolerogenic treatments.
  • Humoral response to drugs:
    Determination of specific anti-drug antibodies by ELISA or immunoluminescence (real-time).
  • Centralisation of results and support in data analysis: multidimensional analysis, phenograms, meta-clustering of lymphocyte subpopulations.

The Biobank is attached to 2 external committees:

    Sección 1 Solicitante:

    • Sección 2 Proyecto:

    • Sección 3 Muestras: